Gut beneficial bacteria have co-evolved with their vertebrate hosts, including fish, over
millions of years. This enduring symbiotic relationship has thrived through natural selection
because these microbiota offer crucial protection against significant threats, notably
infectious diseases. A key component of this interaction involves the bacteria in the gut
microbiota producing the glycan alpha-Gal, which in turn stimulates the host to generate
natural anti-alpha-Gal antibodies.
Recently, a team of researchers—including several co-founders of microXpace—made a
groundbreaking discovery regarding these antibodies. They found that natural anti-alpha-Gal
antibodies have the capability to neutralize major pathogens affecting fish. This research has
also paved the way for innovations in modulating the natural immune response to alpha-Gal.
By enhancing this response, it is possible to prime the fish's immune system, putting it into a
'ready-to-fight' state that offers protection against multiple pathogens simultaneously.
Solution
microXpace, in collaboration with our biotech partner Lallemand, is leveraging patented
technology to develop a suite of products designed to simultaneously protect fish from major
parasitic and infectious diseases. Our flagship product, AquaGalX, is an environmentally
friendly feed additive that is completely safe for use. Extensively tested across various fish
species, AquaGalX has demonstrated significant efficacy in controlling anemia induced by
parasites. This allows fish not only to maintain health but also to grow and gain weight more
effectively.